The first weekend of the 2022 NCAA Tournament bracket provided all the excitement and pageantry we wanted. As we enter the 2022 March Madness Sweet 16, the slipper still fits for No. 15 seed Saint Peter’s. The Peacocks shocked Kentucky in the first round and put together an impressive wire-to-wire performance over Murray State. Now, Saint Peter’s will have another difficult test against No. 3 seed Purdue in Philadelphia, just 90 miles south of Saint Peter’s campus in Jersey City.
The latest 2022 NCAA Tournament odds from Caesars Sportsbook lists the Boilermakers as 12.5-point favorites, but Saint Peter’s was an 18.5-point underdog against Kentucky and an eight-point underdog against Murray State. Which side should you back as you make your 2022 March Madness bets and NCAA Tournament Sweet 16 predictions? All of the 2022 NCAA Tournament lines for the March Madness Sweet 16 are listed below, and SportsLine’s advanced computer model has all the college basketball betting advice and predictions you need to make the best Sweet 16 picks now.
The SportsLine Projection Model simulates every Division I college basketball game 10,000 times. Over the past five-plus years, the proprietary computer model has generated an impressive profit of over $1,300 for $100 players on its top-rated college basketball picks against the spread. Anyone who has followed it has seen huge returns.
The model absolutely crushed its March Madness picks last tournament, beating over 92 percent of all CBS Sports brackets for the second time in three years. The model also nailed a whopping three teams in the Final Four last year.
Now, it has turned its attention to the latest 2022 NCAA Tournament odds and locked in picks for every Sweet 16 matchup. Head to SportsLine now to see every pick.
Top 2022 NCAA Tournament Sweet 16 predictions
One of the model’s strongest Sweet 16 picks is that Gonzaga (-8.5) covers the spread against Arkansas. The No. 1 overall seed in the NCAA Tournament 2022 bracket survived early scares in the first two rounds, allowing No. 16 seed Georgia State to hang around into the second half and needing to overcome a 12-point deficit to beat No. 9 seed Memphis.
Eric Musselman’s Arkansas squad generally likes to play fast, which will play right into Gonzaga’s hands. The Bulldogs rank sixth in the nation in adjusted tempo (72.4) and first in adjusted offensive efficiency (122.1), points per game (87.7) and field-goal shooting percentage (52.6). After a week to recover from a pair of slow starts, the model likes Gonzaga to come out of the gates strong and cover the spread in 70 percent of simulations.
Another one of its 2022 NCAA Tournament predictions: The Miami Hurricanes (-2.5) cover against the Iowa State Cyclones. The Hurricanes put on a show against the No. 2 seed Auburn Tigers on Sunday, securing a 79-61 victory.
Miami’s Charlie Moore stuffed the stat sheet in the win over the Tigers, recording 15 points, nine rebounds, eight assists and three steals. Moore has now scored at least 15 points in his last four games, keying a Miami offense that is averaging just 9.3 turnovers per game, the sixth-best mark in college basketball. The Hurricanes will have ample opportunities on the offensive end of the floor, as the Cyclones rank 326th in the nation in defensive rebounds per game (22.65). According to SportsLine’s model, Miami is covering the spread 60 percent of the time.
How to make 2022 NCAA Tournament picks
The model has also made the call on who will win and cover every other Sweet 16 matchup and has identified a No. 1 seed that goes down hard. It also says an underdog wins outright well over 60 percent of the time. You can only get every pick for every game at SportsLine.
So which NCAA Tournament picks can you make with confidence, and which underdog is a must-back? Check out the latest Sweet 16 odds below, then visit SportsLine to see which teams win and cover the spread, all from a proven computer model that has crushed its college basketball picks, and find out.
NCAA Tournament Sweet 16 odds, spreads, lines
Gonzaga vs. Arkansas (+8.5, 154.5)
Michigan vs. Villanova (-5, 135)
Texas Tech vs. Duke (+1, 136.5)
Houston vs. Arizona (-2, 145)
Saint Peter’s vs. Purdue (-12.5, 135.5)
Providence vs. Kansas (-7.5, 141.5)
North Carolina vs. UCLA (-2, 142)
Iowa State vs. Miami (-2.5, 133)
